Abstract
Cardiac function measured by a Swan-Ganz catheter during hemodialysis (HD) of 12 diabetic patients (ON group) was compared with that of 18 non-diabetic patients (non-DN group). Double product (DP, oxygen consumption index), left ventricular stroke work index (SWI) and systemic vascular resistance index (SVRI) were evaluated prior to and each hour after HD began. Results showed; 1) The mean DP, SWI and SVRI before HD did not differ significantly between the groups. 2) The relationship between %DP (the rate of variation expressed as a % of the pre-HD value) and %SWI (expressed identically) revealed a high positive correlation coefficient in both groups, and the regression coefficient of %SWI to %DP was lower (p<0.05) in the DN group (0.40 vs. 0.97). 3) The regression coefficient of %SVRI (expressed identically) to %SWI was positive in the N group, and different (p<0.005) from that of the non-ON group which expressed negative (+0.44 vs. -0.27). The lower increasing %SWI rate associated with %DP increase, and the decreasing tendency of %SVRI (which was expected to increase in order to compensate for the decreasing %SWI) contribute to hypotension in the diabetic patient with CRP during HD.
