Abstract
Ex vivo evaluation on the non-thrombogenic properties of polyether-segmented nylon 610 was made in terms of estimating changes in the number and adhesiveness of circulating platelets with the construction of arteriovenous shunt in rabbit. The copolymers with particular microstructure exhibited unique feature toward eliminating the activation of contacted and/or adsorbed platelets on their surfaces, which indicates the control of crystalline-amorphous microstructure as the promising concept for the molecular design of non-thrombogenic materials with semicrystalline states.
