Abstract
Clinical study was undertaken to investigate effect on cardiac function and metabolism by pulsatile flow and counterpulsation with PBP 20 system during and after cardiopulmonary bypass in 16 infants under 6 years of age.
The results were as follows. Pulsatile bypass group was less required electrical defibrillation after aortic declamp and more than moderate dose of catecholamine after cardiopulmonary bypass. CK-MB was significantly lower in pulsatile bypass group compared to control group on operative day and 1st postoperative day. Endocardial viability ratio was significantly decreased in control group after cardiopulmonary bypass. But there was no difference of myocadial oxygen intake between two groups. Therefore, pulsatile bypass with this method could improve cardiac function during and after open heart surgery in infants.
