Abstract
We investigated the number and size of the particles (diameter:>2μm) in the extracorporeal circuit by means of particle counter. We also evaluated the efficacy of pre-bypass filters in the extracorporeal circuit. In vitro tests, the removal efficiency of PP3802 and H-600 were 99.3% and 63.8% respectively after rinsing for 5 minutes. In thee clinical cases, mean number of the particle in the cardiopulmonary products after 5 minutes rinsing was 4287±836 pcs/ml. After using PP3802, it dropped to 52±11 pcs/ml. It is describle to use the PP3802 pre-bypass filter for rinsing all cardiopulmonary products before operation.