Abstract
The detrimental alterations occurring in the erythrocyte during cardiopulmonary bypass (CPB) were studied from the viewpoint of erythrocyte deformability. And the relation between the incidence of postoperative complications and the values of erythrocyte deformability after CPB was comparatively examined. 27 cases which were underwent ardiovascular surgery with CPB during May, 1985 to October, 1986 were examined. Erythrocyte deformability was determined by modifying Reid's microfilter method, and red cell filtration rate (ERR) was calculated. Before CPB, ERR was 78.5±12.6ul/sec. During CPB, if CPB was done over than 60minutes, the values dropped significantly from that of before CPB. And postoperative complication of the liver, kidney and heart was observed more frequently in the cases which those values of after CPB dropped more than 20% from the values of before CPB. In contrast, in the cases which CPB was done over than 120minutes if ERR was not disturbed so much, postoperative complications occurred very rare. Therefore, the monitoring of ERR is a useful mean for the judging of microcirculatory disturbance in tissues and for the expecting the occurrence of postoperative complications.
