置換型全人工心臓の動物実験成績の向上の為の改良点の検討

妙中 義之; 高野 久輝; 高谷 節雄; 梅津 光生; 木下 正之; 野田 裕幸; 巽 英介; 矢倉 明彦; 中谷 武嗣; 阿久津 哲造

doi:10.11392/jsao1972.17.849

IMPROVEMENT THE RESULTS OF ANIMAL EXPERIMENTS OF TOTAL ARTIFICIAL HEART

Y. TAENAKA, H. TAKANO, S. TAKATANI, M. UMEZU, M. KINOSHITA, H. NODA, E. TATSUMI, A. YAGURA, T. NAKATANI, T. AKUTSU

Author information

Y. TAENAKA
National Cardiovascular Center Research Institute
H. TAKANO
National Cardiovascular Center Research Institute
S. TAKATANI
National Cardiovascular Center Research Institute
M. UMEZU
National Cardiovascular Center Research Institute
M. KINOSHITA
National Cardiovascular Center Research Institute
H. NODA
National Cardiovascular Center Research Institute
E. TATSUMI
National Cardiovascular Center Research Institute
A. YAGURA
National Cardiovascular Center Research Institute
T. NAKATANI
National Cardiovascular Center Research Institute
T. AKUTSU
National Cardiovascular Center Research Institute

Keywords: total artificial heart, surgical procedure, screw-in type connector, pump design, surgical results

JOURNAL FREE ACCESS

1988 Volume 17 Issue 3 Pages 849-852

DOI https://doi.org/10.11392/jsao1972.17.849

Details

Abstract

In order to improve the results of total artificial heart (TAH) animal experiments, improvement of the surgical procedure to implant the TAH, employment of screw-in type connectors coupling a TAH with the natural tissue and rearrangement of the in- and outflow ports of the pump for adequate fitting were carried out. The cardiopulmonary bypass time was shortened to 164 min after the changes from 245 min before the improvement. The survival duration was prolonged to 18, 68 and 81 days. The degree of thrombus formation around the new type connectors was significantly reduced.

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