Abstract
The twenty six dogs were subjected to 3hours of LAD occlusion. After releare of occlusion, Group I (n=8) had 1 hour reperfusion without LHB, Group II (n=8) had 1 hour reperfusion with LHB and Group II (n=10) had 10 minutes' RBCR on V-A bypass followed by 40 minutes' reperfusion with LHB. Significant improvement of percent recovery of regional contractility, expressed as percent control systolic shortening, was observed in Group III compared with Group I and II (38.4% in G III versus 7.1% in GI and 14.0% G II P<0.05). And significant impovement of limitation of myocardial infarct size was recognized in Group III (AN/AR; 39.0% in G III versus 69.5% in G I and 61.4% in G II, P<0.01) The present data suggests that both RBCR and LHB during reperfusion after LAD occlusion would provide improvement of left ventricular function and limitation of myocardial infarct size.
