CIRCULATORY ASSIST WITHOUT ANTICOAGULATION-EXPERIMENTAL AND CLINICAL STUDIES USING HEPARIN-COATED TUBE AND ROLLER PUMP SYSTEM

Abstract

The experiment of left heart bypass for 24 hours using heparin-coated tube and roller pump system was performed in eight dogs. Platelet counts, ACT and FDP were measured during the experiment. There was a slight decrease of platelet counts at the end of the experiment. After the experiment the dogs were sacrificed, and the autopsy findings revealed no evidence of thromboembolism. The clinical use of this circulatory-assisting system was done in five cases (four cases that could not be weaned from CPB, and one case with severe postoperative LOS). Four patients were successfuly weaned from this mechanical assist. This system is effective without anticoagulants, and the postoperative bleeding can be minimized.