補助循環中の減負荷心における心機能評価法に関する基礎的検討 ―コンダクタンスカテーテルを用いた圧容積関係からの検討―

松若 良介; 松田 暉; 中埜 粛; 大谷 正勝; 笹子 佳門; 高見 宏; 松木 修; 加藤 雅明; 正井 崇史; 川島 康生

doi:10.11392/jsao1972.18.448

EXPERIMENTAL EVALUATION OF THE LINEARIZED FRANK-STALING RELATIONSHIP(LFSR) IN UNLOADED LEFT VENTRICLE UNDER ASSISTED CIRCULATION IN DOGS

R. MATSUWAKA, H. MATSUDA, S. NAKANO, M. OHTANI, Y. SASAKO, H. TAKAMI, O. MATSUKI, M. KATO, T. MASAI, Y. KAWASHIMA

Author information

R. MATSUWAKA
First Department of Surgery, Osaka University Medical School
H. MATSUDA
First Department of Surgery, Osaka University Medical School
S. NAKANO
First Department of Surgery, Osaka University Medical School
M. OHTANI
First Department of Surgery, Osaka University Medical School
Y. SASAKO
First Department of Surgery, Osaka University Medical School
H. TAKAMI
First Department of Surgery, Osaka University Medical School
O. MATSUKI
First Department of Surgery, Osaka University Medical School
M. KATO
First Department of Surgery, Osaka University Medical School
T. MASAI
First Department of Surgery, Osaka University Medical School
Y. KAWASHIMA
First Department of Surgery, Osaka University Medical School

Keywords: Left ventricular function, Assisted circulation, Conductance catheter, Linearized Frank-Starling relationship

JOURNAL FREE ACCESS

1989 Volume 18 Issue 2 Pages 448-451

DOI https://doi.org/10.11392/jsao1972.18.448

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Abstract

The applicability of LFSR to assess the left ventricular function under unloaded conditions was studied in seven canine heart under CPB(n=4) and left heart bypass(LHB, n=3). Instantaneous pressure-volume(P-V) data utilizing micromanometer and conductance catheter was obtained during transient(15sec) acute volume loading under CPB and LHB. The correlation(r) between stroke work determined as P-V curve area and end diastolic volume was high as ranging from 0.967 to 0.991. This highly linear relationship indicated that LFSR may be applicable to the partially unloaded left ventricle under assisted circulation.

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