Abstract
Newly developed compact portable centrifugal pump for assist circulation has been evaluated as to its basic properties and performance in vitro and in vivo tests. With the adoption of rotary sealing, the pump attained noleakage running over 200 hours under the condition of 5000rpm and outlet pressure of 120mmHg in vitro tests. It also showed acceptably small extent of hemolysis under the same condition. However in animal tests employing adult dogs, unacceptable hemolysis was observed especially when out flow of the pump was considerably reduced due to high artery pressure and poor blood supply to the pump, whereas LAP, CVP, AP and RBC, WBC, PLT, Ht, erythrocyte fragility (EF) remained almost constant. Further improvement and long term animal tests are necessary to prove its feasibility for clinical application.
