1989 Volume 18 Issue 3 Pages 1191-1194
The three different sterilizations (EOG, Autoclave and γ-Ray) for hemophan membrane were studied in eight patients on maintenance hemodialysis. In the changes of white blood cells, platelets, platelet factor-4, β-thromboglobuhn and activated coagulation time during the hemodialysis, there were no significant differences in the three sterilizations. In autoclave dialyser, changes of C3a and factor XII were slightly greater than in other sterilizations. Ultra filtration rate was decreased in γ-ray sterilization. No differences were seen in clearance of small molecules in the three sterilizations. The results show that autoclave and γ-ray steri-lization make some influence on membrane structure of hemophan.