Abstract
Miniaturized left ventricular assist device in which the chamber has 3-5 ml in capacity and the orfice of the ballvalve has 4 mm in diameter has been tested in 35 dogs. In these experiments, the orfice of the inflow duct was made as follows. (1) made of silicon rubber. (2) coated with gelatin and treated with glutaraldehyde. (3) covered with goretex graft. (4) coated with cardiothene. (5) connected a piece of glutaraldehyed-treated aorta of dog. Thrombus formation at the orfice of inflow duct in left atrium was found in every group except group 5.