Abstract
Hemofiltration and hemodialysis with various substitution fluid or dialysate (acetate or bicarbonate, sodium and buffer concentration), were performed for investigating solutes removal. The ratios of solutes reduction space for BUN reduction space were greater in hemofiltration than in hemodialysis. Alternatins of body fluid osmolarity or pH had no influences on solutes removal existing in total body water (BUN, Creatinine, Uric acid) nor on solutes removal existing in extracellular space (B2-MG, Inuline). Intracellular solutes (Pi, K) removal was changed by pH and kinds of buffers. For the adequate removal of various, solutes, ultrafiltration method should be applied and composition of substitution fluid or dialysate should be into consideration.
