Abstract
In an experimental study to prevent bacterial contamination in peritoneal dialysis (PD) by using catheters with percutaneous access devices (PAD) made of hydroxyapatite (HAp), two dogs couldsuccessfully survive for a long time (19 and 6 months) without any peritoneal or so-called ‘tunnel’ infection. One dog, in which we caused end-stage renal failure by subtotal ligation of the left renal arteries with the right nephrectomy, could survive for more than 6 months, and this long-term survival of an experimental uremic dog may be a world record. Long-term experiment of end-stage renal failure dog should contribute to many kinds of study about peritonial dialysis treatment.
