Abstract
A new method for countering the number of adhered platelets on polymer surfaces to evaluate their nonthrombogenicity was developed by using the assay of their adenines in the adhered platelets. This method is simple with high sensitivity and good reproducibility. Moreover, the method is applicable for a wide range of polymers with various properties and shapes. The platelets adhered on the biocompatible copolymers having 2-methacryloyloxyethyl phosphorylcholine (MPC) moiety were compared with those on the conventional materials by this method. It was reconfirmed that the MPC copolymers suppressed effectively the adhesion and activation of platelets.
