Abstract
Experimental studies on latissimus dorsi cardiomyoplasty. To obtain maximal augmentation of cardiac function on cardiomyoplasty with latissimus dorsi in acute heart failure state, experimental studies were performed using 24 mongrel dogs. First of all, adequate stimulation mode were evaluated by ejection fraction on left ventriculogram and improvement of arterial pressure and cardiac out-put in acute heart failure, induced by multiple ligations of the branches of left coronary arteries. Subsequently, hemodynamic effects according to different wrapping directions of the latissimus dorsi muscle flap were evaluated. It was considered that burst synchronous pacing improved the left ventricular function. And optimal delay time of the stimulation was 100 msec and optimal pulse duration time was 100 msec. And clockwise direction of the total wrapping of the both ventricles was effective to improve the hemodynamics as compared with counter-clock-wise direction of the wrapping method.
