Abstract
Continuous hemofiltration (CHF) is accepted as an alternative method to conventional hemodialysis for treating acute renal failure in critically ill patients with unstable hemodynamics. However, solute removal of CHF depends on convection alone, higher ultrafiltration volume up to 20l or more is required to attain adequate control of uremia for severe catabolic patients. For there patients, we attempted to apply 6hr continuous venovenous hemodialysis (CVVHD) combined with CHF. A dialysis flow rate of 26.4 ml/min made it possible to increase the creatinine clearence to 19.1ml/min. Daily Cr increase was also significantly supressed. These results indicate that CVVHD with CHF possesses superior capacity for solute removal to CHF alone.
