Clinical evaluation of the new PES hemoconcentrator LH-420 P

Abstract

A new hemoconcentrator (LH-420 P) was employed to control plasma volume in 30 patients during cardiopulmonary bypass operation. LH-420 P was made of polyethersulfone membrane, and had a smaller priming volume than the current model (Hemocon®). At 350-400 torr and a flow rate of 250-300 ml/min, the ultrafiltration rate was 82.4±27.3 ml/min, which was 1.8 times higher than Hemocon®. The permeable properties of the blood components were equal to those of the previous device, and blood cells and plasma proteins were concentrated with ease. Thus, LH-420 P was useful for plasma water removal by ultrafiltration in association with cardiopulmonary bypass.