Abstract
Ion implantations into silicone rods were performed at 150 keV with doses ranging from 1×1017 to 3×1017 ions/cm2. The non-thrombogenicity was tested by the superior vena cava (SVC) indwelling method for two days in rats with In-111-tropolone-platelets, and by the inferior vena cava (IVC) indwelling method. Results of the SVC indwelling method showed that platelet accumulation on ion implanted specimens decreased. Macroscopic views of the ion-implanted IVC specimens in dogs revealed little thrombus formation. In particular, SVC indwelling method revealed that O2+, K+, and Kr+ (1×1017 ions/cm2) implantation was most effective in reducing platelet accumulation.
