Abstract
A new pulse generator for experimental cardiomyoplasty was developed. The size and weight of this pulse generator were 115×60×23mm and 197 grams. Cardiomyoplasty using the lattissimus dorsi muscle flap (LDMF) was carried out on 7 mongrel dogs' normal heart and the LDMF was driven by this pulse generator. The hemodynamic changes were evaluated during stimulation. The arterial, pulmonary arterial, pulmonary capillary wedge and the right atrial pressures significantly ascended, and the cardiac index increased with a statistical significance. The newly developed pulse generator worked well for stimulation of the LDMF in acute experiments and chronic experimental use was warranted.
