Development of continuous recirculation peritoneal dialysis

Abstract

As a new dialysis system, continuous recirculation peritoneal dialysis(CRPD) was introduced in order to improve solute removal efficiency. In CRPD, patient's dialysate in peritoneal cavity was extracorporated through a double-lumen catheter and purified by an out-side dialyzer. From an canine ex vivo study, urea peritoneal and dialyzer dialy-sances were 3.05 and 33.3 ml/min under 100 and 200 ml/min of recirculation and dialysate flow rates using FB-50H(0.5 m²). From these results, weekly urea clearance was estimated as 115.51/week in 12 hr/day CRPD superior to 70.01/week of conven-tional CAPD and 99.81/week of 12 hr/week HD.