Abstract
The recent devised hemodialysis machines are usually equipped with ultrafiltration controllers to facilitate the use of high-flux dialyzers, and they are greatly contributed to blood purification therapy. However, the number of components has increased, which has led to complications in the systems. It has been attemped that the system has now been simplified by reducing the number of components without spoiling the high-accuracy of ultrafiltration control, even then the high-flux dialyzer is used. The new ultrafiltration control system has only one third the working parts of the conventional system, and trouble-prone parts(pump, electromagnetic valve, etc.) have been reduced by half also. The system's basic operation is the transmembrane pressure(TMP) control. The TMP is measured on the dialysate flowing state, not during ECUM, which makes possible to gain the high-accuracy ultrafiltration. In vivo, the high-accuracy ultrafiltration controls (-73.6±101g(N=45) for 3448±747g average ultrafiltration volume) was obtained using of the high-flux dialyzer.
