Abstract
We clarified that Clq·β2-MG complexes are significantly higher and Clq·SAP complexes are significantly lower in the sera of hemodialysisassociated amyloidosis patients. In this report these complexes were measured before and after hemodialysis and in vitro experiments were done to research absorption of these complexes to dialysis membrane. Clq·β2-MG complexes and Clq·SAP complexes got elevated after hemodialysis (HD) when Cu membrane was used. On the other hand Clq·β2-MG complexes and Clq·SAP complexes got lower after HD when PAN membrane was used.Absorption of these complexes to PAN membrane was suggested from in vitro experiments. So it was speculated that these complexes got lower mainly because of absorption to dialysis membrane.
