Abstract
Ventricular systolic function and myocardial energetic efficiency were assessed in reperfused dog hearts after 30 minutes ischemia which were heterotopically transplanted. Myocardial oxygen consumption under unloaded condition returned to normal after 60 minutes of reperfusion. However, venricular function indexed as preload recruitable stroke work (PRSW) and myocardial energetic efficiency were 75% and 78% of the control at 18 hours after ischemia. This unloaded reperfused heart may be a useful model for assessing ventricular performance and energetic efficiency in failing hearts.
