Abstract
A new membrane oxygenator (LH-760) was developed and assessed for gas transfer and blood compatibility. The oxygenator is made of silicone hollow fiber. Therefore this oxygenator may have a constant gas exchange performance and a superior blood compatibility to other oxygenators made of microporous mambrane. This device was used to conduct cardiopulmonary bypass (CPB) in 10 patients. Blood gas analysis and hematological examination were carried out during CPB. Blood gas was maintained at high PO2 and acceptable PCO2 levels throughout CPB. Platelet count at the end of CPB was maintained at 75% of the initial value. Fibrinogen decreased temporarily following the start of CPB and
then recovered by the end of CPB. FOP increased during the early period of CPB but did not change there after. C3a increased during CPB while C3, C4, CH50 showed little change. These findings show this oxygenator has adequate gas exchange and good blood compatibility.
