Comparative analysis of mechanical and biological properties of a pure collagen coated ultrafine polyester fiber graft versus Gelseal® graft

Abstract

We have developed a pure collagen coated ultrafine polyester fiber graft (CUFPG), which was cross-linked by a hydrophilic polyepoxy compound. CUFPG was compared with the Gelseal Triaxial® graf t in several properties. Porosity was Oml in both prosthesis. The quantity of impregnated gelatin in Gelseal® was seven times that of collagen in CUFPG. In addition, the gelatin of Gelseal® was easily detached from the inner surface and it had 11.33pg/cm² endotoxin at 37°C 72 hours in pyrogen test. On the other hand, the collagen of CUFPG did not detached and it had no endotoxin. In a cell culture study there was no remarkable difference in cell growth on both prosthesis. In conclusion, CUFPG is thought to be a more safety vascular prosthesis more than the graft sealed with gelatin “Gelseal Triaxial®”.