Abstract
It is known that in long-term perfusion there is a decline in the gas transfer performance of a membrane oxygenator due to the plasma leakage and the absorption of plasma protein on the surface of microporous membrane. We experienced the same decline in the gas transfer performance and made a fundamental experiment with high freqency jet ventilator (HFJV) instead of gas blender and gas flow meter to prevent the “ Wet Lung”. The oxygenation in 200-400/min vibration with HFJV is significantly better than that without HFJV. Then we applied this HFJV clinically and even in the long-term perfusion (182hrs. ) the ABGA was excellent and we didn't need to exchange the membrane oxygenator. This is our only clinical experience and it is suggested that HFJV could prevent the “ Wet Lung” and the decline in the gas transfer performance even in the long-term perfusion.
