Abstract
The purpose of this study is to evaluate the effect of mechanical circulation using pulsatile or nonpulsatile blood pump to shock organs. Methods: Damaged liver was produced by clamping descending aorta clamping at infra-diaphragm in 14 dogs. After 60 minutes of ischemia, LA-FA bypass was started. Pneumatic pulsatile pump (TOYOBO) was used in 7 dogs (Gr.-PP) and centrifugal pump (Biomedicus) in 7 (Gr.-NPP). In both groups the mean arterial pressure was kept at 80mmHg. Mean bypass flow was 96±14ml/kg/min in Gr.-PP, 95±35ml/kg/min in Gr.-NPP. Results: In the both groups the bile flow and arterial keton body ratio (AKBR) decreased significantly after ischemia, and recovered to normal level after 90min of LA-FA bypass. There were no significant difference between the two groups. Conclusion: These results suggested that nonpulsatile circulatory assist is as effective to recover the shock liver as pulsatile circulatory assist.
