Abstract
A new hemoconcentrator (LH-840 P: JMS) was employed to control plasma volume during open heart surgery with cardiopulmonary bypass. LH-840P is made of polyethersulfone membrane. We clinically evaluated LH-840P in comparison with HC-100M: MERA. Twenty patients who undergoing elective valvular surgery were divided into two groups: LH-840P group (group L: 10 patients) and HC-100M(group H: 10 patients). Age, body weight, cardiopulmonary bypass time were not significantly different between the two groups. The ul trafiltration ratio of HC-100M was significantly higher than that of LH-840P. The sieving coefficient of LH-840P to albumin, direct-bilirubin, free-hemoglobin were significantiy lower than those of HC-100M. However, serum free-hemoglobin just after CPB showed no significant difference between the two groups. We speculated that this was caused by the adsorption of bilirubin to the hollow fiber of LH-840P which has been demonstrated in in vitro analysis. The new hemoconcentrator (LH-840P) was effective and safe in non-hemic primed extracorporeal circulation.
