Abstract
Sieving characteristics in HF with high ultrafiltration were examined during an experimental study using an aqueous solution involving myoglobin. Significant conclusions were obtained as follows: A value of apparent sieving coefficient (SC) decreased with increasing blood flow rate (QB) under a constant filtration flow rate(QF) because a higher shear rate of blood flow reduced a thickness of concentration polarization layer. A SC value also decreased with QF increase in low filtration fraction (FF) due to developing concentration polarization with increasing QF value. On the other hand, a SC value increased with QF in higher FF filtration because of stronger solute condensation along the blood side stream.
