Abstract
The effect of fluid mechanical stress on hemolysis. In this paper we describe an experimental study of the effect of fluid mechanical stress on hemolysis in artificial organs. In order to investigate the effect of an impact failure on red blood cells, in-vitro tests and flow visualization tests were performed by using extra corporeal circuit. The results are as follows: 1) The tracer collided against the inner surface of the visualization model under the condition of high flow rates. 2) The rate of hemolysis increased if the velocity of blood flow against the surface was more than 300cm/s. There suggest that the impact failure of red blood cells might be playing a major role in the hemolysis.
