Abstract
Exprimental evolutionary studies is proposed in this paper by means of trilateral research combining phylogenyontogeny, biomechanics, and molecular genetics. Through this new research method the correlation between inheritance and immune system is studied and a new concept for immunology as cytological digestion system is also proposed. Combining biomechanical stimuli with biomaterials in animal, experimental evolutionary study was carried out. Hybrid type artificial organ inducing hemopoietic bone marrow tissue could be successfully developed using hydroxyapatite chamber not only in mammals but sharks, which is relict of archetype without bone marrow tissue in internal skeletons. Cementoblasts could be also induced biomechanically. In these new methods, in vivo culture of liver and pancreas in hydroxyapatite chamber was carried out.
