Abstract
In our current study, we found that the rate of hemolysis was related to the collision stream (more 300cm/sec) against the inner surface of extra-corporeal circulation devices. In order to estimate the occurrence of collision stream against the inner surface, we made rough surface area in a centrifugal pump. The surface roughness existed near the outlet domain and on the impeller. In addition, the effect of collision stream was estimated from the relationship between the pump rotational speed and the rate of hemolysis. The results of those in-vitro tests were showed as follows. When the pump rotated in low speed, there did not exist the relation between the rate of hemolysis and the surface roughness in an outlet domain and surface of an impeller. On the other hands, when the pump rotated on high speed, we found that the rate of hemolysis increased outlet domain.
In conclusion, the collision stream toward a particular part affected on the rate of hemolysis.
