Abstract
The factors influencing systemic vascular resistance(SVR) during cardiopulrrnnary bypass (CPB) were evaluated in 39 patients who underwent cardiac surgery(CAB:15, valve surgery: 19). There was no change in SVR during CPB between CABG and valve surgery. In the patients having CABG, additional evaluation was performed. The increased SVR was related to an older age and concomitant diabetes mellitus. Isoflurane strongly decreased SVR. Immediately after separation from CPB, low hematocrit value, which resulted fran the delay of timing of hemoconcentration, became one of the causes of decreased SVR.In the patients having CABG with isoflurane anesthesia, and also with low hematocrit value after weaning off CPB, an adequate use of vasoconstrictor is required.