Abstract
Lymphocytapheresis is a useful treatment for immunological diseases and immunological modulation. However, this treatment is not easy and the cost is high. In this study, we examined a new lymphocytapheresis using non woven polyester for transfusion. One treatment was arteriovenous circulation, and the other was venous-venous transfusion bag system. Lymphocytes were reduced to 50%. T-cells and B-cells were detected about 50% from blood. The activated T-cells were adsorbed and their number was 50%. The VV method was superior to the AV method in effectiveness, safety and easy treatment. The VV transfusion bag method should be considered with other treatments such as the immunoadsorbtion system. Lymphocytapheresis using Finecell will be a very useful treatment for immunological diseases and extra-corporeal immunomodulation.
