Jinko Zoki
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
Estimation of biocompatibility of vitamin E modified regenerated cellulose membrane by oxidized LDL in haemodialysis patients
Yasuhiko FUKUDAHideki OHDANYoshio OHSHIROIssei TANAKA
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JOURNAL FREE ACCESS

1998 Volume 27 Issue 2 Pages 480-483

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Abstract
Clinical effect and significance of the modified cellulose membrane which is fixed with vitamin E (α-tocopherol) on inner surface (CL-EE) have not been clear.
Oxidized LDL(Ox-LDL)was investigated in 64 haemo-dialysis patients. The significant correlation between the high incidence of complication of atherosclerotic diseases and the high elevation rate of Ox-LDL during haemodialysis.
CL-EE was used for 3 months to the 13 patients who's Ox-LDL elevatcd 140% or more during haemodialysis at the screening test. Their post-haemodialysis level and the elevation rate of Ox-LDL reduced dramatically by CL-EE.
These results indicate the possibility of Ox-LDL elevation rate during haemodialysis as indication for CL-EE usage.
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© The Japanese Society for Artificial Organs
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