Abstract
In order to enhance the solute removal efficiency of a dialyzer, several types of IFEHD have been introduced for clinical applications. In this paper, the effectiveness of IFEHD was examined during an analytical and an experimental study. As a result of the analytical study, the maximum internal filtration flow rate was increased in a dialyzer with a smaller fiber diameter (D), a larger fiber length (Leff) and a larger fiber density ratio (FDR). The results of an in vitro evaluation using myoglobin solution showed the same tendencies as those of the analytical study. Development of a dialyzer for IFEHD, however, should take into account the patient's safety.
