Abstract
We have further appreciated the clinical features of REDY SYSTEM—new type of sorbent-based artificial kidney.
REDY has fine ability of correcting metabolic acidosis of uremic patients. The sources of bicarbonate are dialysate and infusate acetate, and the hydrogen ions are removed by zirconium phosphate in the form of anmonium ions.
Dialysate ammonia concentration do not exceed 2.7mg/dl, so it may be safely used in the patients of normal hepatic function.
The dialysances of small molecule substances are somewhat inferior compared to usual single pass method, because of low QD (200ml/min).
In the course of experiments, so called disequilibrium syndrome is seldom encountered.