Abstract
A new arterio graft was made by treating a swine carotid artery with chymotrypsin, proteiolytic enzyme, and by tanning it by glutalaldehyde. Chymotrypsin has no effects on elastines and a graft maintains its elasticity. Immunological assay and animal experiments confirmed the safety and function. The graft was clinically used in 102 dialysis patients at their limbs for blood access. The most cuccessful patient could use a graft for 24 months. The grafts of 40 of the 102 patients functioned or functioned with problems for more than 12 months. The remained cases were transplanted again. Clinical advantages of the graft are that it permits fast hemostasis and rarely develops aneurysm.
