Abstract
It has been known that hemofiltration is more phisiological than other available procedure for reduction of uremic products.
Present in vitro study was undertaken to qualitatively evaluate hemofiltration method, and to clarify qualitative difference between predilution and postdilution method.
Solutes in ultrafiltrated sera were divided by molecular filtration method with Sephadex G15. Amicon Diaflo Membrane PM10 (10, 000), PM30 (30, 000) and XM50 (50, 000) was used to ultrafiltrate uremic diluted or nondiluted sera.
Results were as follows;
1. Chromatogram pattern of the ultrafiltrated sera did not changed according to the dilution of sera.
2. If molecular cut-off point of ultrafilter increased, a new peak was showned on the chromatogram.
3. However, such cases belonged to the minority group.