Abstract
Rapid decrease of toxins by the direct hemoperfusion may necessitate the consideration of the mass transfer mechanism within the body. The mass transfer model used in this study has been shown to be suitable for thr performance evaluation of the direct HP.and the evaluation of relation between amount of adsorbent and clearance. When the exit concentration of a solute remains zero in the adsorber, clearance is equal to the blood flow rate. It was also found that the new 2-pool model using a new parameter MKfAv fully described the solute transfer phenomena within the body of the reanal failure dogs.