Abstract
Freeze-dried umblical cord veins were used for vascular substitute. The umblical cord vessels have been treated with various suspending medium such as 3% and 5% glutamic acid sodium, 5% glutamic acid sodium contained 0.6% pepton and 0.2% ascorbic acid, 10% and 20% DMSO before freezedrying. As the suspending medium, 5% glutamic acid sodium contained 0.6% pepton and 0.2% ascorbic acid was best in view of surface characterization, antithrombogenicity and immunological antigenecity. The freeze-dried human umblical cord vein graft was experimentally replaced to parts of canine abdominal aorta and inferior vena cava. Ten of 20 showed patent more than fourty-five days. The antibody product after transplantation of the graft was not detected by Ouchterlony's method.
