Abstract
The object of this study is to account for the effect of dialysate recirculation on the transport of uremic toxins through analysis of 3-pool model, which is made up of intracellular fluid, extracellular fluid and dialysate tank.
The good agreement between in vitro data, in vivo data and theoretical value gives the optimum operating conditions determining the appropriate dialysate recirculating therapy. It has become apparent that the dialysate recirculating therapy is more effective for protection of disequilibrium syndrome, stable dialysis, mild dialysis, and stability of blood pressure and osmotic pressure compared with dialysate single pass therapy.
This fact was well confirmed by theoretical analysis based on 3-pool model.
