A New Artificial Liver Support System

Abstract

A new type of artificial liver support system which was composed of two different sized hollow fibers was made in our clinical department.
Large pore sized hollow fiber consisted of the plasma separating apparatus can pass through the moderate molecular substances and small molecular substances such as electrolytes were reabsorbed by smaller pore sized hollow fiber.
This system was utilized for animal experiments successfully.
Bilirubin and transaminase in serum were reduced and there were no remarkable changes in the electrolytes.
Molar ratio was raised significantly.
Three patients suffered from hepatic coma were treated by this system and reduction of bilirubin was satisfactory even if we lost three of them.