Abstract
The infectious agent in serum hepatitis is not clearly defined, but the presence of hepatitis B antigen (hepatitis B virus) is an indicator of potential infectivity.
This report represented the study on immunoadsorption of HBs-antigen from HBs-antigen positive serum by means of sepharose immobilized HBs-antibody. The removal of HBs-antigen from serum was performed in batch process and column affinity process.
The results were as follows:
1. Immobilized HBs-antibody is able to adsorb specifically HBs-antigen.
2. High adsorbent rate is gained by immobilizing HBs-antibody which has more pure and more active immunological potency.
3. Immunoadsorbent method is exceedingly superior to non-specific adsorbent method such as activated charcoal.
