Abstract

We have recently developed the SND system with a safety air trup chamber and hemonipper due to the ideas that (1) total blood volume in a dialyser should be same as in DND system, and (2) both volume and occasion of the blood recirculation should be as minimum as possible. In this paper, the feasibility of the SND system for the long term hemodialysis in two patients was studied in comparison with an ordinary SND system. 5hr dialysis for our SND system was applied owing to the pre-experimental result that 5hr hemodialysis was sufficient enough for its performance, compared with 7-8hr (6hr, in this paper) dialysis necessary for the ordinary SND system. Other experimental conditions were the same as were applied to the ordinary SND.
Compared with the ordinary SND, our SND revealed, in spite of 1hr shorter dialysis, that (a) in both patients the average of the initial BUN and creatinie levels were 10% lower, (b) CTR was also 5% lower and (c) hematocrit was conspicuously increased especially in one patient. The increase of hematocrit may result from the reduction of the negative blood pressure, one of the important improvements in our SND system, in the blood lines. The reasons why our SND system do function so well may reside in the realization of the ideas (1) and (2). This feature will be also explained briefly in this paper.