Abstract
The lifetimes of immobilized UK on sulfonated poly vinylidene fluoride (PVDF) films and silicone·ollagen graft were measured.
UK activity immobilized on PVDF films became undetectable at 70th day with 40 days half lifetime. On the other hand, UK activity immobilized on silicone·collagen graft tubes was still active at 210 days with 180 days half lifetime. The lifetime of 350 days was extrapolated from the decay curve. The patency of the graft tube implanted in the aorta of a dog was clearly observed at 360th day by the angiography.
The amount of immobilized UK on silicone·collagen graft depended on the process of chemical treatment.
