Abstract
The materials of vascular prosthesis was discussed in the respect of the healing process of the implantation. The author maintains that vascular prosthesis must have properties of an antithrombogenecity in the early stage of the implantation and an affinity to the connective tissue in the long term.
In the experiments of implantation of vascular prosthesis made from antithrombogenic substances, good patency rate was obtained in the early stage and the surface of the prosthesis removed was covered with a thin layer of proteins, however, pannus formation was observed at the anastomotic lines in every cases of long term. The tendency of the endothelization against the foreign body (vascular prosthesis) was very firm, and the prosthesis have to keep preventing the endothelization for all time. While in the case of vascular prosthesis which have no antithranbogenecity, the prosthesis was tended to be obstructed by thrombus. However, once the endothelization was established, the prosthesis keep patent with the assistance of thromboresistance of endothelium. The materials of the prosthesis was encapsulated with connective tissue under the endothelium.
From these results, the author propose the properties of vascular prosthesis mentioned above.
