Ultra-thin and small nanopore fabrication using photothermal-etching method for molecular detection

Abstract

Nanopore measurement is a method for the label-free detection and analysis of single biomolecules passing through nano-sized pores. Nanopores are broadly classified into protein and solid-state nanopores. Protein nanopore-based DNA sequencers have garnered significant attention as next-generation sequencers. Conversely, research advancements in solid-state nanopores, which entered the field more recently, have demonstrated significant progress in recent years. This review article outlines solid-state nanopore fabrication methods and introduces a novel photothermal-etching-assisted nanopore fabrication method.