2026 Volume 2026 Article ID: 260302
Fluorescent nanodiamonds with nitrogen-vacancy (NV) centers are emerging as versatile quantum sensors at room temperature. They enable the assessment of temperature, magnetic fields, and biochemical environments inside living systems. This article reviews recent progress in biological applications, including intracellular thermometry in cells and organisms, and integration with on-chip devices. Challenges associated with the improvement of material quality, such as extending spin coherence, are discussed along with future perspectives for applying nanodiamond quantum sensors in the life sciences and medicine.